Prof Krish Nirantharakumar 

Krish is the Joint Director for the Centre for Health Data Science and Professor in Health Data Science and Public Health at University of Birmingham, UK. Krish’s research interest spans across methodology development in epidemiology to clinical research in diabetes, endocrinology, women’s health and multimorbidity. Krish’s unique innovative methodological programme of work, known as “Automated Clinical Epidemiology Studies (ACES)”, has led to the University of Birmingham gaining an international reputation for being one of the few universities globally to have successfully researched and knowledge-engineered epidemiological study designs into computer executable formats. University of Birmingham was the first to implement such a platform in the United Kingdom and publish the methods in a peer-reviewed epidemiology journal. The software within the ACES platform, named DExtER (Data Extraction for Epidemiological Research) has resulted in more than 100 peer-reviewed original research publications and has raised over 20 million pounds worth of research funding in the last 3 years.  

Prof.Krish Nirantharakumar

MBBS, MPH, MD, FFPH, FRCP

Director (Joint) of Centre for Health Data Science 

Professor of Health Data Science and Public Health | Honorary Consultant in Public Health Medicine 

University of Birmingham |  University Hospitals Birmingham Foundation Trust | UK Health Security Agency 

Adjunct Professor
k.nirantharan@bham.ac.uk
Google ScholarResearchGate
URL to Institutional Repository
Positions
Qualifications
Publications
Research Interests

Jul 2021 –

Professor of Health Data Science and Public Health,

University of Birmingham

Feb 2023 –

Joint Director for Centre for Health Data Science

University of Birmingham

Jun 2022 –

Deputy Director for Institute of Applied Health Research

University of Birmingham

Apr 2022  –

Turing Fellow

Alan Turing Institute

Apr 2013 –

Honorary Consultant in Public Health Medicine

 

Uk Health Security Agency / Public Health England

Sep 2014 –

Honorary Consultant in Public Health Medicine

Department of Diabetes, University Hospitals Birmingham NHS Foundation Trust

Feb 2018 – Feb 2021

UKRI Innovation Clinical Fellow

 

Health Data Research UK

Mar 2014 – Jun 2021

Senior Clinical Lecturer

University of Birmingham

Mar 2013 – Feb 2014

Senior Clinical Research Fellow

 

University of Warwick

Mar 2012 – Feb 2013

Clinical Research Fellow

University of Birmingham

Aug 2007 –  Feb 2012

Specialty Registrar  in Public Health Medicine

 

Health Protection Unit, Walsall Primary Care Trust & University of Birmingham

Aug 2005 –  Aug 2007

Senior House Officer in Clinical Medicine

 

Sandwell and West Birmingham NHS Trust

Aug 2004 –Aug 2005

Foundation Year 2

University Hospital of North Staffordshire

 

Feb 2003  –Feb 2004

House Officer

National Hospital of Sri Lanka

Aug 2002 – Jan 2003

Demonstrator

(Obstetrics & Gynaecology)

Department of Obstetrics and Gynaecology, University of Colombo, Sri Lanka

May 2002 – Aug 2002

Screening Medical Officer

S.Thomas’ College, Mt. Lavinia, Sri Lanka

2013

Doctor of Medicine (MD)

Thesis title: Clinical decision support systems in the care of hospitalized patients with diabetes

 

University of Birmingham

2012

Certificate of Completion of Training (CCT) in Public Health Medicine

 

West Midlands Deanery

2010

Membership of the Faculty of Public Health (MFPH)

 

Faculty of Public Health

2008

Master of Public Health (MPH)

 

University of Birmingham

2008

Postgraduate Diploma in Epidemiology

(PGDip. Epi)

 

London School of Hygiene and Tropical Medicine

 

2007

Membership of the Royal College of Physicians (MRCP)

 

Royal College of Physicians

2002

Bachelor of Medicine, Bachelor of Surgery (MBBS)

University of Colombo, Sri Lanka

PEER-REVIEWED JOURNAL PUBLICATIONS

He has published over 125 original research articles and several correspondence, editorial, literature review, or protocol papers. Almost 75% of all publications, including high-impact publications, were in the last 5 years.  Therefore, he expects an exponential increase in his citation in the next few years, as evidenced by the trajectory (citations in 2017: 188; 2018:316; 2019:465; 2020: 761; & 2021: 1406). His total number of citations is 5267, and H-index is 42 (Mar 2023).

 

PRINCIPAL RESEARCH PUBLICATIONS 

  1. Braithwaite T, Subramanian A, Petzold A, Galloway J, Adderley NJ, Mollan SP, Plant GT, Nirantharakumar K#, Denniston AK. Trends in Optic Neuritis Incidence and Prevalence in the UK and Association with Systemic and Neurologic Disease. JAMA Neurol. 2020;77(12):1-11.
  2. Subramanian A, Nirantharakumar K*, Hughes S, Myles P, Williams T, Gokhale KM, Taverner T, Chandan JS, Brown K, Simms-Williams N, Shah AD, Singh M, Kidy F, Okoth K, Hotham R, Bashir N, Cockburn N, Lee SI, Turner GM, Gkoutos GV, Aiyegbusi OL, McMullan C, Denniston AK, Sapey E, Lord JM, Wraith DC, Leggett E, Iles C, Marshall T, Price MJ, Marwaha S, Davies EH, Jackson LJ, Matthews KL, Camaradou J, Calvert M, Haroon S. Symptoms and risk factors for long COVID in non-hospitalized adults. Nat Med. 2022;28(8):1706-14.
  3. Thayakaran R, Adderley NJ, Sainsbury C, Torlinska B, Boelaert K, Sumilo D, Price M, Thomas GN, Toulis KA, Nirantharakumar K#*. Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study. BMJ. 2019;366:l4892.
  4. Okoth K, Chandan JS, Marshall T, Thangaratinam S, Thomas GN, Nirantharakumar K#*, Adderley NJ. Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review. BMJ. 2020;371:m3502.
  5. Adderley NJ, Nirantharakumar K*, Marshall T. Risk of stroke and transient ischaemic attack in patients with a diagnosis of resolved atrial fibrillation: retrospective cohort studies. BMJ. 2018;361:k1717.
  6. Šumilo D, Nirantharakumar K, Willis BH, Rudge GM, Martin J, Gokhale K, Thayakaran R, Adderley NJ, Chandan JS, Okoth K, Harris IM, Hewston R, Skrybant M, Deeks JJ, Brocklehurst P. Long term impact of prophylactic antibiotic use before incision versus after cord clamping on children born by caesarean section: longitudinal study of UK electronic health records. BMJ. 2022;377:e069704.
  7. Caleyachetty R, Thomas GN, Toulis KA, Mohammed N, Gokhale KM, Balachandran K, Nirantharakumar K#. Metabolically Healthy Obese and Incident Cardiovascular Disease Events among 3.5 Million Men and Women. Journal of the American College of Cardiology. 2017;70(12):1429-37.
  8. Riley J, Antza C, Kempegowda P, Subramanian A, Chandan JS, Gokhale K, Thomas N, Sainsbury C, Tahrani AA, Nirantharakumar K. Social Deprivation and Incident Diabetes-Related Foot Disease in Patients With Type 2 Diabetes: A Population-Based Cohort Study. Diabetes care. 2021;44(3):731-9.
  9. Singh P, Adderley N, Subramanian A, Gokhale K, Singhal R, Toulis KA, Bellary S, Nirantharakumar K*#, Tahrani AA. The Impact of Bariatric Surgery on Incident Microvascular Complications in Patients With Type 2 Diabetes: A Matched Controlled Population-Based Retrospective Cohort Study. Diabetes care. 2021;44(1):116-24.
  10. Singh P, Adderley NJ, Hazlehurst J, Price M, Tahrani AA, Nirantharakumar K*#, Bellary S. Prognostic Models for Predicting Remission of Diabetes Following Bariatric Surgery: A Systematic Review and Meta-analysis. Diabetes care. 2021;44(11):2626-41.
  11. Kumarendran B, O’Reilly MW, Subramanian A, Šumilo D, Toulis K, Gokhale KM, Wijeratne CN, Coomarasamy A, Tahrani AA, Azoulay L, Arlt W, Nirantharakumar K. Polycystic Ovary Syndrome, Combined Oral Contraceptives, and the Risk of Dysglycemia: A Population-Based Cohort Study With a Nested Pharmacoepidemiological Case-Control Study. Diabetes care. 2021;44(12):2758-66.
  12. Adderley NJ, Subramanian A, Toulis K, Gokhale K, Taverner T, Hanif W, Haroon S, Thomas GN, Sainsbury C, Tahrani AA, Nirantharakumar K#. Obstructive Sleep Apnea, a Risk Factor for Cardiovascular and Microvascular Disease in Patients with Type 2 Diabetes: Findings from a Population-Based Cohort Study. Diabetes care. 2020;43(8):1868-77.
  13. Tracy A, Subramanian A, Adderley NJ, Cockwell P, Ferro C, Ball S, Harper L, Nirantharakumar K#. Cardiovascular, thromboembolic and renal outcomes in IgA vasculitis (Henoch-Schönlein purpura): a retrospective cohort study using routinely collected primary care data. Annals of the rheumatic diseases. 2019;78(2):261-9.
  14. Subramanian A, Adderley NJ, Tracy A, Taverner T, Hanif W, Toulis KA, Thomas GN, Tahrani AA, Nirantharakumar K#. Risk of Incident Obstructive Sleep Apnoea among Patients with Type 2 Diabetes. Diabetes care. 2019;42(5):954-63.
  15. Krishna MT, Subramanian A, Adderley NJ, Zemedikun DT, Gkoutos GV, Nirantharakumar K#. Allergic diseases and long-term risk of autoimmune disorders: longitudinal cohort study and cluster analysis. Eur Respir J. 2019;54(5).
  16. Harvey PR, Thomas T, Chandan JS, Mytton J, Coupland B, Bhala N, Evison F, Patel P, Nirantharakumar K#*, Trudgill NJ. Incidence, morbidity and mortality of patients with achalasia in England: findings from a study of nationwide hospital and primary care data. Gut. 2019;68(5):790-5.
  17. Chandan JS, Thomas T, Gokhale KM, Bandyopadhyay S, Taylor J, Nirantharakumar K#. The burden of mental ill health associated with childhood maltreatment in the UK, using The Health Improvement Network database: a population-based retrospective cohort study. Lancet Psychiatry. 2019;6(11):926-34.
  18. Adderley NJ$, Subramanian A$, Nirantharakumar K$, Yiangou A, Gokhale KM, Mollan SP, Sinclair AJ. Association between Idiopathic Intracranial Hypertension and Risk of Cardiovascular Diseases in Women in the United Kingdom. JAMA Neurol. 2019;76(9):1088-98.
  19. Kumarendran B, O’Reilly MW, Manolopoulos KN, Toulis KA, Gokhale KM, Sitch AJ, Wijeyaratne CN, Coomarasamy A, Arlt W, Nirantharakumar K#*. Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database. PLoS medicine. 2018;15(3):e1002542.
  20. Daly B, Toulis KA, Thomas N, Gokhale K, Martin J, Webber J, Keerthy D, Jolly K, Saravanan P, Nirantharakumar K#*. Increased risk of ischemic heart disease, hypertension, and type 2 diabetes in women with previous gestational diabetes mellitus, a target group in general practice for preventive interventions: A population-based cohort study. PLoS medicine. 2018;15(1):e1002488.
  21. Nirantharakumar K$*, Hemming K, Narendran P, Marshall T, Coleman JJ. A prediction model for adverse outcome in hospitalized patients with diabetes. Diabetes care. 2013;36(11):3566-72.
  22. King D, Thomas T, Chandan JS, Bhala N, Adderley NJ, Nirantharakumar K, Trudgill N. Achalasia Is Associated With Atopy in Patients Younger Than 40 Years of Age. Am J Gastroenterol. 2020.
  23. Alshehri Z, Subramanian A, Adderley NJ, Gokhale KM, Karamat MA, Ray CJ, Kumar P, Nirantharakumar K, Tahrani AA. Risk of incident obstructive sleep apnoea in patients with type 1 diabetes: a population-based retrospective cohort study. Diabetologia. 2022;65(8):1353-63.
  24. Gooden TE, Gardner M, Wang J, Chandan JS, Beane A, Haniffa R, Taylor S, Greenfield S, Manaseki-Holland S, Thomas GN, Nirantharakumar K. The risk of mental illness in people living with HIV in the UK: a propensity score-matched cohort study. Lancet HIV. 2022;9(3):e172-e81.
  25. Lee SI, Cooper J, Fenton A, Subramanian A, Taverner T, Gokhale KM, Phillips K, Patel M, Harper L, Thomas GN, Nirantharakumar K. Decreased renal function is associated with incident dementia: An IMRD-THIN retrospective cohort study in the UK. Alzheimers Dement. 2022.
  26. Prete A, Subramanian A, Bancos I, Chortis V, Tsagarakis S, Lang K, Macech M, Delivanis DA, Pupovac ID, Reimondo G, Marina LV, Deutschbein T, Balomenaki M, O’Reilly MW, Gilligan LC, Jenkinson C, Bednarczuk T, Zhang CD, Dusek T, Diamantopoulos A, Asia M, Kondracka A, Li D, Masjkur JR, Quinkler M, Ueland G, Dennedy MC, Beuschlein F, Tabarin A, Fassnacht M, Ivović M, Terzolo M, Kastelan D, Young WF, Jr., Manolopoulos KN, Ambroziak U, Vassiliadi DA, Taylor AE, Sitch AJ, Nirantharakumar K, Arlt W. Cardiometabolic Disease Burden and Steroid Excretion in Benign Adrenal Tumors : A Cross-Sectional Multicenter Study. Ann Intern Med. 2022;175(3):325-34.
  27. Ho IS, Azcoaga-Lorenzo A, Akbari A, Black C, Davies J, Hodgins P, Khunti K, Kadam U, Lyons RA, McCowan C, Mercer S, Nirantharakumar K, Guthrie B. Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies. Lancet Public Health. 2021;6(8):e587-e97.

 

All other publications

  1. Gokhale KM, Chandan JS, Toulis K, Gkoutos G, Tino P, Nirantharakumar K#*. Data extraction for epidemiological research (DExtER): a novel tool for automated clinical epidemiology studies. Eur J Epidemiol.
  2. Adderley NJ, Subramanian A, Perrins M, Nirantharakumar K, Mollan SP, Sinclair AJ. Headache, Opiate Use, and Prescribing Trends in Women With Idiopathic Intracranial Hypertension: A Population-Based Matched Cohort Study. Neurology. 2022.
  3. Adderley NJ, Taverner T, Price MJ, Sainsbury C, Greenwood D, Chandan JS, Takwoingi Y, Haniffa R, Hosier I, Welch C, Parekh D, Gallier S, Gokhale K, Denniston AK, Sapey E, Nirantharakumar K. Development and external validation of prognostic models for COVID-19 to support risk stratification in secondary care. BMJ open. 2022;12(1):e049506.
  4. Almulhem M, Thayakaran R, Hanif S, Gooden T, Thomas N, Hazlehurst J, Tahrani AA, Hanif W, Nirantharakumar K. Ramadan is not associated with increased infection risk in Pakistani and Bangladeshi populations: Findings from controlled interrupted time series analysis of UK primary care data. PloS one. 2022;17(1):e0262530.
  5. Benson RA, Okoth K, Keerthy D, Gokhale K, Adderley NJ, Nirantharakumar K, Lasserson DS. Analysis of the relationship between sex and prescriptions for guideline-recommended therapy in peripheral arterial disease, in relation to 1-year all-cause mortality: a primary care cohort study. BMJ open. 2022;12(3):e055952.
  6. Chapman R, Haroon S, Simms-Williams N, Bhala N, Miah F, Nirantharakumar K, Ferguson J. Socioeconomic deprivation, age and language are barriers to accessing personal health records: a cross-sectional study of a large hospital-based personal health record system. BMJ open. 2022;12(1):e054655.
  7. Gokhale K, Mostafa SA, Wang J, Tahrani AA, Sainsbury CA, Toulis KA, Thomas GN, Hassan-Smith Z, Sapey E, Gallier S, Adderley NJ, Narendran P, Bellary S, Taverner T, Ghosh S, Nirantharakumar K, Hanif W. The clinical profile and associated mortality in people with and without diabetes with Coronavirus disease 2019 on admission to acute hospital services. Endocrinol Diabetes Metab. 2022;5(1):e00309.
  8. Gokhale KM, Adderley NJ, Subramanian A, Lee WH, Han D, Coker J, Braithwaite T, Denniston AK, Keane PA, Nirantharakumar K. Metformin and risk of age-related macular degeneration in individuals with type 2 diabetes: a retrospective cohort study. Br J Ophthalmol. 2022.
  9. Gooden TE, Chandan JS, Taylor S, Nirantharakumar K, Thomas GN. Mental health needs of adolescents with HIV in Africa – Authors’ reply. Lancet HIV. 2022;9(6):e376-e7.
  10. Gooden TE, Gardner M, Wang J, Jolly K, Lane DA, Benjamin LA, Mwandumba HC, Kandoole V, Lwanga IB, Taylor S, Manaseki-Holland S, Lip GYH, Nirantharakumar K, Thomas GN. Incidence of Cardiometabolic Diseases in People With and Without Human Immunodeficiency Virus in the United Kingdom: A Population-Based Matched Cohort Study. J Infect Dis. 2022;225(8):1348-56.
  11. Gooden TE, Wang J, Zemedikun DT, Taylor S, Greenfield S, Manaseki-Holland S, Nirantharakumar K, Thomas GN. A matched cohort study investigating premature, accentuated, and accelerated aging in people living with HIV. HIV Med. 2022.
  12. Greenwood D, Taverner T, Adderley NJ, Price MJ, Gokhale K, Sainsbury C, Gallier S, Welch C, Sapey E, Murray D, Fanning H, Ball S, Nirantharakumar K, Croft W, Moss P. Machine learning of COVID-19 clinical data identifies population structures with therapeutic potential. iScience. 2022;25(7):104480.
  13. Ho IS, Azcoaga-Lorenzo A, Akbari A, Davies J, Hodgins P, Khunti K, Kadam U, Lyons R, McCowan C, Mercer SW, Nirantharakumar K, Guthrie B. Variation in the estimated prevalence of multimorbidity: systematic review and meta-analysis of 193 international studies. BMJ open. 2022;12(4):e057017.
  14. Lee SI, Azcoaga-Lorenzo A, Agrawal U, Kennedy JI, Fagbamigbe AF, Hope H, Subramanian A, Anand A, Taylor B, Nelson-Piercy C, Damase-Michel C, Yau C, Crowe F, Santorelli G, Eastwood KA, Vowles Z, Loane M, Moss N, Brocklehurst P, Plachcinski R, Thangaratinam S, Black M, O’Reilly D, Abel KM, Brophy S, Nirantharakumar K#*, McCowan C#. Epidemiology of pre-existing multimorbidity in pregnant women in the UK in 2018: a population-based cross-sectional study. BMC Pregnancy Childbirth. 2022;22(1):120.
  15. Mostafa SA, Mena SC, Antza C, Balanos G, Nirantharakumar K, Tahrani AA. Sleep behaviours and associated habits and the progression of pre-diabetes to type 2 diabetes mellitus in adults: A systematic review and meta-analysis. Diab Vasc Dis Res. 2022;19(3):14791641221088824.
  16. Narendran P, Tomlinson C, Beese S, Sharma P, Harris I, Adriano A, Maggs F, Burrows M, Nirantharakumar K, Thomas N, Price MJ, Andrews RC, Moore DJ. A systematic review and meta-analysis of interventions to preserve insulin-secreting β-cell function in people newly diagnosed with type 1 diabetes: Results from intervention studies aimed at improving glucose control. Diabetic medicine : a journal of the British Diabetic Association. 2022;39(1):e14730.
  17. Nichols L, Taverner T, Crowe F, Richardson S, Yau C, Kiddle S, Kirk P, Barrett J, Nirantharakumar K, Griffin S, Edwards D, Marshall T. In simulated data and health records, latent class analysis was the optimum multimorbidity clustering algorithm. J Clin Epidemiol. 2022.
  18. Okoth K, Crowe F, Marshall T, Thomas GN, Nirantharakumar K, Adderley NJ. Sex-specific temporal trends in the incidence and prevalence of cardiovascular disease in young adults: a population-based study using UK primary care data. Eur J Prev Cardiol. 2022;29(10):1387-95.
  19. Okoth K, Subramanian A, Chandan JS, Adderley NJ, Thomas GN, Nirantharakumar K, Antza C. Long term miscarriage-related hypertension and diabetes mellitus. Evidence from a United Kingdom population-based cohort study. PloS one. 2022;17(1):e0261769.
  20. Phillips K, Subramanian A, Thomas GN, Khan N, Chandan JS, Brady P, Marshall T, Nirantharakumar K, Fabritz L, Adderley NJ. Trends in the pharmacological management of atrial fibrillation in UK general practice 2008-2018. Heart (British Cardiac Society). 2022;108(7):517-22.
  21. Santos IS, Lotufo PA, Goulart AC, Brant LCC, Pinto Filho MM, Pereira AC, Barreto SM, Ribeiro ALP, Thomas GN, Lip GYH, Bensenor IM, Arasalingam A, Beane A, Bensenor IM, Brocklehurst P, Cheng KK, El-Bouri W, Feng M, Goulart AC, Greenfield S, Guo Y, Guruparan M, Gusso G, Gooden TE, Haniffa R, Humphreys L, Jolly K, Jowett S, Kumarendran B, Lancashire E, Lane DA, Li X, Lip Co-Pi GYH, Li YG, Lobban T, Lotufo PA, Manseki-Holland S, Moore DJ, Nirantharakumar K, Olmos RD, Paschoal E, Pirasanth P, Powsiga U, Romagnolli C, Santos IS, Shantsila A, Sheron VA, Shribavan K, Szmigin I, Subaschandren K, Surenthirakumaran R, Tai M, Neil Thomas Co-Pi G, Varella AC, Wang H, Wang J, Zhang H, Zhong J. Cardiovascular Health and Atrial Fibrillation or Flutter: A Cross-Sectional Study from ELSA-Brasil. Arq Bras Cardiol. 2022.
  22. Sharma-Oates A, Zemedikun DT, Kumar K, Reynolds JA, Jain A, Raza K, Williams JA, Bravo L, Cardoso VR, Gkoutos G, Nirantharakumar K, Lord JM. Early onset of immune-mediated diseases in minority ethnic groups in the UK. BMC Med. 2022;20(1):346.
  23. Sheron VA, Shanmugathas S, Gooden TE, Guruparan M, Kumarendran B, Lip GYH, Manaseki-Holland S, Nirantharakumar K, Shribavan K, Subaschandren K, Haniffa R, Surenthirakumaran R, Thomas GN, Uruthirakumar P, Greenfield S, Lane DA, Beane A. Healthcare provider and patient perspectives on access to and management of atrial fibrillation in the Northern Province, Sri Lanka: a rapid evaluation of barriers and facilitators to care. BMC Health Serv Res. 2022;22(1):1078.
  24. Singh P, Adderley NJ, Subramanian A, Gokhale K, Hazlehurst J, Singhal R, Bellary S, Tahrani AA, Nirantharakumar K. Glycemic outcomes in patients with type 2 diabetes after bariatric surgery compared with routine care: a population-based, real-world cohort study in the United Kingdom. Surg Obes Relat Dis. 2022.
  25. Subramanian A, Gokhale K, Sainsbury C, Nirantharakumar K, Toulis KA. Sodium-glucose cotransporter-2 inhibitors and the risk of gout in patients with type 2 diabetes mellitus: A propensity-score-matched, new-user design study with an active comparator using the IQVIA Medical Research Data UK database. Diabetes, obesity & metabolism. 2022.
  26. Subramanian A, Han D, Braithwaite T, Thayakaran R, Zemedikun DT, Gokhale KM, Lee WH, Coker J, Keane PA, Denniston AK, Nirantharakumar K, Azoulay L, Adderley NJ. Angiotensin-converting enzyme inhibitors and risk of age-related macular degeneration in individuals with hypertension. Br J Clin Pharmacol. 2022;88(9):4199-210.
  27. Subramanian A, Lee SI, Phillips K, Toulis KA, Kempegowda P, O’Reilly MW, Adderley NJ, Thangaratinam S, Arlt W, Nirantharakumar K. Polycystic ovary syndrome and risk of adverse obstetric outcomes: a retrospective population-based matched cohort study in England. BMC Med. 2022;20(1):298.
  28. Šumilo D, Nirantharakumar K, Willis BH, Rudge GM, Martin J, Gokhale K, Thayakaran R, Adderley NJ, Chandan JS, Okoth K, Harris IM, Hewston R, Skrybant M, Deeks JJ, Brocklehurst P. Long-term impact of pre-incision antibiotics on children born by caesarean section: a longitudinal study based on UK electronic health records. Health Technol Assess. 2022;26(30):1-160.
  29. Thayakaran R, Goel R, Adderley NJ, Chandan JS, Zemedikun D, Nirantharakumar K, Harper L. Cluster analysis of patients with granulomatosis with polyangiitis (GPA) based on clinical presentation symptoms: a UK population-based cohort study. Arthritis Res Ther. 2022;24(1):201.
  30. Umar N, King D, Chandan JS, Bhala N, Nirantharakumar K, Adderley N, Zemedikun DT, Harvey P, Trudgill N. The association between inflammatory bowel disease and mental ill health: a retrospective cohort study using data from UK primary care. Aliment Pharmacol Ther. 2022;56(5):814-22.
  31. Vitalis A, Nirantharakumar K, Thayakaran R, Vohra RK, Kay M, Shantsila A, Lip GYH. The Impact of Atrial Fibrillation on Outcomes of Peripheral Arterial Disease: Analysis of Routinely Collected Primary Care Data. Am J Med. 2022;135(4):488-92.
  32. Wang Z, Hazlehurst J, Subramanian A, Tahrani AA, Hanif W, Thomas N, Singh P, Wang J, Sainsbury C, Nirantharakumar K, Crowe FL. Diabetic Foot Risk Classification at the Time of Type 2 Diabetes Diagnosis and Subsequent Risk of Mortality: A Population-Based Cohort Study. Front Endocrinol (Lausanne). 2022;13:888924.
  33. Zemedikun DT, Lee H, Nirantharakumar K, Raza K, Chandan JS, Lord JM, Jackson TA. Comorbidity phenotypes and risk of mortality in patients with osteoarthritis in the UK: a latent class analysis. Arthritis Res Ther. 2022;24(1):231.
  34. Aiyegbusi OL, Hughes SE, Turner G, Rivera SC, McMullan C, Chandan JS, Haroon S, Price G, Davies EH, Nirantharakumar K, Sapey E, Calvert MJ. Symptoms, complications and management of long COVID: a review. J R Soc Med. 2021;114(9):428-42.
  35. Almulhem M, Chandan JS, Gokhale K, Adderley NJ, Thayakaran R, Khunti K, Tahrani AA, Hanif W, Nirantharakumar K. Cardio-metabolic outcomes in South Asians compared to White Europeans in the United Kingdom: a matched controlled population-based cohort study. BMC Cardiovasc Disord. 2021;21(1):320.
  36. Akiboye F, Sihre HK, Al Mulhem M, Rayman G, Nirantharakumar K, Adderley NJ. Impact of diabetes specialist nurses on inpatient care: A systematic review. Diabetic medicine : a journal of the British Diabetic Association. 2021;38(9):e14573.
  37. Bhachu HK, Cockwell P, Subramanian A, Adderley NJ, Gokhale K, Fenton A, Kyte D, Nirantharakumar K, Calvert M. Impact of Using Risk-Based Stratification on Referral of Patients With Chronic Kidney Disease From Primary Care to Specialist Care in the United Kingdom. Kidney Int Rep. 2021;6(8):2189-99.
  38. Braithwaite T, Adderley NJ, Subramanian A, Galloway J, Kempen JH, Gokhale K, Cope AP, Dick AD, Nirantharakumar K, Denniston AK. Epidemiology of Scleritis in the United Kingdom From 1997 to 2018: Population-Based Analysis of 11 Million Patients and Association Between Scleritis and Infectious and Immune-Mediated Inflammatory Disease. Arthritis Rheumatol. 2021;73(7):1267-76
  39. Chandan JS, Keerthy D, Gokhale KM, Bradbury-Jones C, Raza K, Bandyopadhyay S, Taylor J, Nirantharakumar K. The association between exposure to domestic abuse in women and the development of syndromes indicating central nervous system sensitization: A retrospective cohort study using UK primary care records. Eur J Pain. 2021;25(6):1283-91.
  40. Chandan JS, Subramanian A, Chandan JK, Gokhale KM, Vitoc A, Taylor J, Bradbury-Jones C, Bandyopadhyay S, Nirantharakumar K. The risk of COVID-19 in survivors of domestic violence and abuse. BMC Med. 2021;19(1):246.
  41. Chandan JS, Thomas T, Raza K, Bradbury-Jones C, Taylor J, Bandyopadhyay S, Nirantharakumar K. Intimate Partner Violence and the Risk of Developing Fibromyalgia and Chronic Fatigue Syndrome. J Interpers Violence. 2021;36(21-22):Np12279-np98.
  42. Chandan JS, Zemedikun DT, Thayakaran R, Byne N, Dhalla S, Acosta-Mena D, Gokhale KM, Thomas T, Sainsbury C, Subramanian A, Cooper J, Anand A, Okoth KO, Wang J, Adderley NJ, Taverner T, Denniston AK, Lord J, Thomas GN, Buckley CD, Raza K, Bhala N, Nirantharakumar K, Haroon S. Nonsteroidal Antiinflammatory Drugs and Susceptibility to COVID-19. Arthritis Rheumatol. 2021;73(5):731-9.
  43. Fox J, Khan O, Curtis H, Wright A, Pal C, Cockburn N, Cooper J, Chandan JS, Nirantharakumar K. Rapid translation of clinical guidelines into executable knowledge: A case study of COVID-19 and online demonstration. Learn Health Syst. 2021;5(1):e10236.
  44. Goel R, Chandan JS, Thayakaran R, Adderley NJ, Nirantharakumar K, Harper L. Cardiovascular and Renal Morbidity in Takayasu Arteritis: A Population-Based Retrospective Cohort Study From the United Kingdom. Arthritis Rheumatol. 2021;73(3):504-11.
  45. Haider S, Thayakaran R, Subramanian A, Toulis KA, Moore D, Price MJ, Nirantharakumar K. Disease burden of diabetes, diabetic retinopathy and their future projections in the UK: cross-sectional analyses of a primary care database. BMJ open. 2021;11(7):e050058.
  46. Haroon S, Subramanian A, Cooper J, Anand A, Gokhale K, Byne N, Dhalla S, Acosta-Mena D, Taverner T, Okoth K, Wang J, Chandan JS, Sainsbury C, Zemedikun DT, Thomas GN, Parekh D, Marshall T, Sapey E, Adderley NJ, Nirantharakumar K. Renin-angiotensin system inhibitors and susceptibility to COVID-19 in patients with hypertension: a propensity score-matched cohort study in primary care. BMC Infect Dis. 2021;21(1):262.
  47. Keerthy D, Chandan JS, Abramovaite J, Gokhale KM, Bandyopadhyay S, Day E, Marwaha S, Broome MR, Nirantharakumar K, Humpston C. Associations between primary care recorded cannabis use and mental ill health in the UK: a population-based retrospective cohort study using UK primary care data. Psychol Med. 2021:1-10.
  48. King D, Chandan JS, Thomas T, Nirantharakumar K, Reulen RC, Adderley NJ, Trudgill N. The Risk of Later Diagnosis of Inflammatory Bowel Disease in Patients With Dermatological Disorders Associated With Inflammatory Bowel Disease. Inflamm Bowel Dis. 2021;27(11):1731-9.
  49. Kostopoulos G, Doundoulakis I, Antza C, Bouras E, Nirantharakumar K, Tsiachris D, Thomas GN, Lip GYH, Toulis KA. Incident atrial fibrillation in patients with differentiated thyroid cancer: a meta-analysis. Endocr Relat Cancer. 2021;28(5):325-35.
  50. Lai AG, Chang WH, Parisinos CA, Katsoulis M, Blackburn RM, Shah AD, Nguyen V, Denaxas S, Davey Smith G, Gaunt TR, Nirantharakumar K, Cox MP, Forde D, Asselbergs FW, Harris S, Richardson S, Sofat R, Dobson RJB, Hingorani A, Patel R, Sterne J, Banerjee A, Denniston AK, Ball S, Sebire NJ, Shah NH, Foster GR, Williams B, Hemingway H. An informatics consult approach for generating clinical evidence for treatment decisions. BMC medical informatics and decision making. 2021;21(1):281
  51. McKay SC, Lembach H, Hann A, Okoth K, Anderton J, Nirantharakumar K, Magill L, Torlinska B, Armstrong M, Mascaro J, Inston N, Pinkney T, Ranasinghe A, Borrows R, Ferguson J, Isaac J, Calvert M, Perera M, Hartog H. Health-related quality of life, uncertainty and coping strategies in solid organ transplant recipients during shielding for the COVID-19 pandemic. Transpl Int. 2021;34(11):2122-37
  52. Okoth K, Wang J, Zemedikun D, Thomas GN, Nirantharakumar K, Adderley NJ. Risk of cardiovascular outcomes among women with endometriosis in the United Kingdom: a retrospective matched cohort study. Bjog. 2021;128(10):1598-609.
  53. Parretti HM, Subramanian A, Adderley NJ, Abbott S, Tahrani AA, Nirantharakumar K. Post-bariatric surgery nutritional follow-up in primary care: a population-based cohort study. Br J Gen Pract. 2021;71(707):e441-e9.
  54. Parry-Smith W, Okoth K, Subramanian A, Gokhale KM, Chandan JS, Humpston C, Coomarasamy A, Nirantharakumar K, Šumilo D. Postpartum haemorrhage and risk of mental ill health: A population-based longitudinal study using linked primary and secondary care databases. J Psychiatr Res. 2021;137:419-25.
  55. Parry-Smith W, Šumilo D, Subramanian A, Gokhale K, Okoth K, Gallos I, Coomarasamy A, Nirantharakumar K. Postpartum haemorrhage and risk of long-term hypertension and cardiovascular disease: an English population-based longitudinal study using linked primary and secondary care databases. BMJ open. 2021;11(5):e041566.
  56. Rouette J, Yin H, Pottegård A, Nirantharakumar K, Azoulay L. Use of Hydrochlorothiazide and Risk of Melanoma and Nonmelanoma Skin Cancer. Drug Saf. 2021;44(2):245-54.
  57. Subramanian A, Adderley NJ, Gkoutos GV, Gokhale KM, Nirantharakumar K, Krishna MT. Ethnicity-based differences in the incident risk of allergic diseases and autoimmune disorders: A UK-based retrospective cohort study of 4.4 million participants. Clin Exp Allergy. 2021;51(1):144-7.
  58. Subramanian A, Anand A, Adderley NJ, Okoth K, Toulis KA, Gokhale K, Sainsbury C, O’Reilly MW, Arlt W, Nirantharakumar K. Increased COVID-19 infections in women with polycystic ovary syndrome: a population-based study. European journal of endocrinology. 2021;184(5):637-45.
  59. Subramanian A, Idkowiak J, Toulis KA, Thangaratinam S, Arlt W, Nirantharakumar K. Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review. European journal of endocrinology. 2021;184(1):51-64.
  60. Wang J, Cooper JM, Gokhale K, Acosta-Mena D, Dhalla S, Byne N, Chandan JS, Anand A, Okoth K, Subramanian A, Bangash MN, Jackson T, Zemedikun D, Taverner T, Hanif W, Ghosh S, Narendran P, Toulis KA, Tahrani AA, Surenthirakumaran R, Adderley NJ, Haroon S, Khunti K, Sainsbury C, Thomas GN, Nirantharakumar K. Association of Metformin with Susceptibility to COVID-19 in People with Type 2 Diabetes. The Journal of clinical endocrinology and metabolism. 2021;106(5):1255-68.
  61. Welch C….Nirantharakumar K et al. Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study. Age Ageing. 2021;50(3):617-30.
  62. Yang M, He Q, Gao F, Nirantharakumar K, Veenith T, Qin X, Page AT, Wong MCS, Huang J, Kuo ZC, Xia B, Zhang C, He Y, Meng W, Yuan J, Pan Y. Regular use of proton-pump inhibitors and risk of stroke: a population-based cohort study and meta-analysis of randomized-controlled trials. BMC Med. 2021;19(1):316.
  63. Zemedikun DT, Chandan JS, Raindi D, Rajgor AD, Gokhale KM, Thomas T, Falahee M, De Pablo P, Lord JM, Raza K, Nirantharakumar K. Burden of chronic diseases associated with periodontal diseases: a retrospective cohort study using UK primary care data. BMJ open. 2021;11(12):e048296.
  64. Zemedikun DT, Gokhale K, Chandan JS, Cooper J, Lord JM, Filer A, Falahee M, Nirantharakumar K, Raza K. Type 2 diabetes mellitus, glycaemic control, associated therapies and risk of rheumatoid arthritis: a retrospective cohort study. Rheumatology (Oxford). 2021;60(12):5567-75.
  65. Sainsbury C, Wang J, Gokhale K, Acosta-Mena D, Dhalla S, Byne N, Chandan JS, Anand A, Cooper J, Okoth K, Subramanian A, Bangash MN, Taverner T, Hanif W, Ghosh S, Narendran P, Cheng KK, Marshall T, Gkoutos G, Toulis K, Thomas N, Tahrani A, Adderley NJ, Haroon S, Nirantharakumar K#. Sodium-glucose co-transporter-2 inhibitors and susceptibility to COVID-19: A population-based retrospective cohort study. Diabetes, obesity & metabolism. 2021;23(1):263-9.
  66. Wu J, Huang J, Zhu G, Liu Y, Xiao H, Zhou Q, Si X, Yi H, Wang C, Yang D, Chen S, Liu X, Liu Z, Wang Q, Lv Q, Huang Y, Yu Y, Guan X, Li Y, Nirantharakumar K, Cheng K, Peng S, Xiao H. Systemic Corticosteroids and Mortality in Severe and Critical COVID-19 Patients in Wuhan, China. The Journal of clinical endocrinology and metabolism. 2020;105(12).
  67. Wang J, Shen S, Price MJ, Lu J, Sumilo D, Kuang Y, Manolopoulos K, Xia H, Qiu X, Cheng KK, Nirantharakumar K#. Glucose, Insulin, and Lipids in Cord Blood of Neonates and Their Association with Birthweight: Differential Metabolic Risk of Large for Gestational Age and Small for Gestational Age Babies. J Pediatr. 2020;220:64-72.e2.
  68. Vusirikala A, Thomas T, Bhala N, Tahrani AA, Thomas GN, Nirantharakumar K#. Impact of obesity and metabolic health status in the development of non-alcoholic fatty liver disease (NAFLD): A United Kingdom population-based cohort study using the health improvement network (THIN). BMC endocrine disorders. 2020;20(1):96.
  69. Tresoldi AS, Sumilo D, Perrins M, Toulis KA, Prete A, Reddy N, Wass JAH, Arlt W, Nirantharakumar K#. Increased Infection Risk in Addison’s Disease and Congenital Adrenal Hyperplasia. The Journal of clinical endocrinology and metabolism. 2020;105(2):418-29.
  70. Thomas T, Chandan JS, Subramanian A, Gokhale K, Gkoutos G, Harper L, Buckley C, Chandratre P, Raza K, Situnayake D, Nirantharakumar K#. Epidemiology, morbidity and mortality in Behçet’s disease: a cohort study using The Health Improvement Network (THIN). Rheumatology (Oxford). 2020;59(10):2785-95.
  71. Singh P, Subramanian A, Adderley N, Gokhale K, Singhal R, Bellary S, Nirantharakumar K#*, Tahrani AA. Impact of bariatric surgery on cardiovascular outcomes and mortality: a population-based cohort study. Br J Surg. 2020;107(4):432-42.
  72. Sapey E, Gallier S, Mainey C, Nightingale P, McNulty D, Crothers H, Evison F, Reeves K, Pagano D, Denniston AK, Nirantharakumar K, Diggle P, Ball S. Ethnicity and risk of death in patients hospitalised for COVID-19 infection in the UK: an observational cohort study in an urban catchment area. BMJ Open Respir Res. 2020;7(1).
  73. Plant N, Šumilo D, Chapman R, Webber J, Saravanan P, Nirantharakumar K#. Unmet needs of women with GDM: a health needs assessment in Sandwell, West Midlands. J Public Health (Oxf). 2020;42(4):e516-e24.
  74. King D, Reulen RC, Thomas T, Chandan JS, Thayakaran R, Subramanian A, Gokhale K, Bhala N, Nirantharakumar K, Adderley NJ, Trudgill N. Changing patterns in the epidemiology and outcomes of inflammatory bowel disease in the United Kingdom: 2000-2018. Aliment Pharmacol Ther. 2020;51(10):922-34.
  75. Haider S, Sadiq SN, Lufumpa E, Sihre H, Tallouzi M, Moore DJ, Nirantharakumar K#, Price MJ. Predictors for diabetic retinopathy progression-findings from nominal group technique and Evidence review. BMJ Open Ophthalmol. 2020;5(1):e000579.
  76. Daly B, Arroll B, Nirantharakumar K, Scragg RKR. Improved foot management of people with diabetes by primary healthcare nurses in Auckland, New Zealand. N Z Med J. 2020;133(1527):39-50.
  77. Crowe F, Zemedikun DT, Okoth K, Adderley NJ, Rudge G, Sheldon M, Nirantharakumar K, Marshall T. Comorbidity phenotypes and risk of mortality in patients with ischaemic heart disease in the UK. Heart. 2020;106(11):810-6.
  78. Chandan JS, Thomas T, Bradbury-Jones C, Taylor J, Bandyopadhyay S, Nirantharakumar K#*. Risk of Cardiometabolic Disease and All-Cause Mortality in Female Survivors of Domestic Abuse. J Am Heart Assoc. 2020;9(4):e014580.
  79. Chandan JS, Thomas T, Bradbury-Jones C, Russell R, Bandyopadhyay S, Nirantharakumar K#*, Taylor J. Female survivors of intimate partner violence and risk of depression, anxiety and serious mental illness. The British journal of psychiatry. 2020;217(4):562-7.
  80. Chandan JS, Okoth K, Gokhale KM, Bandyopadhyay S, Taylor J, Nirantharakumar K#*. Increased Cardiometabolic and Mortality Risk Following Childhood Maltreatment in the United Kingdom. J Am Heart Assoc. 2020;9(10):e015855.
  81. Chandan JS, Keerthy D, Zemedikun DT, Okoth K, Gokhale KM, Raza K, Bandyopadhyay S, Taylor J, Nirantharakumar K#. The association between exposure to childhood maltreatment and the subsequent development of functional somatic and visceral pain syndromes. EClinicalMedicine. 2020;23:100392.
  82. Chandan JS, Gokhale KM, Bradbury-Jones C, Nirantharakumar K#, Bandyopadhyay S, Taylor J. Exploration of trends in the incidence and prevalence of childhood maltreatment and domestic abuse recording in UK primary care: a retrospective cohort study using ‘the health improvement network’ database. BMJ open. 2020;10(6):e036949.
  83. Almulhem M, Susarla R, Alabdulaali L, Khunti K, Karamat MA, Rasiah T, Tahrani AA, Hanif W, Nirantharakumar K. The effect of Ramadan fasting on cardiovascular events and risk factors in patients with type 2 diabetes: A systematic review. Diabetes Res Clin Pract. 2020;159:107918.
  84. Alhodaib HI, Antza C, Chandan JS, Hanif W, Sankaranarayanan S, Paul S, Sutcliffe P, Nirantharakumar K#. Mobile Clinical Decision Support System for the Management of Diabetic Patients With Kidney Complications in UK Primary Care Settings: Mixed Methods Feasibility Study. JMIR Diabetes. 2020;5(4):e19650.
  85. Akiboye F, Adderley NJ, Martin J, Gokhale K, Rudge GM, Marshall TP, Rajendran R, Nirantharakumar K#, Rayman G. Impact of the Diabetes Inpatient Care and Education (DICE) project on length of stay and mortality. Diabetic medicine. 2020;37(2):277-85.
  86. Toulis KA, Viola D, Gkoutos G, Keerthy D, Boelaert K, Nirantharakumar K#. Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease. Clinical endocrinology. 2019;91(2):323-30.
  87. Thomas T, Chandan JS, Harvey PR, Bhala N, Ghosh S, Nirantharakumar K#*, Trudgill NJ. The Risk of Inflammatory Bowel Disease in Subjects Presenting With Perianal Abscess: Findings From the THIN Database. Journal of Crohn’s & colitis. 2019;13(5):600-6.
  88. Thayakaran R, Perrins M, Gokhale KM, Kumaran S, Narendran P, Price MJ, Nirantharakumar K#*, Toulis KA. Impact of glycaemic control on fracture risk in 5368 people with newly diagnosed Type 1 diabetes: a time-dependent analysis. Diabetic medicine. 2019;36(8):1013-9.
  89. Taverner T, Crowe FL, Thomas GN, Gokhale K, Thayakaran R, Nirantharakumar K#*, Rajabally YA. Circulating Folate Concentrations and Risk of Peripheral Neuropathy and Mortality: A Retrospective Cohort Study in the U.K. Nutrients. 2019;11(10).
  90. O’Reilly MW, Glisic M, Kumarendran B, Subramanian A, Manolopoulos KN, Tahrani AA, Keerthy D, Muka T, Toulis KA, Hanif W, Thomas GN, Franco OH, Arlt W, Nirantharakumar K#. Serum testosterone, sex hormone-binding globulin and sex-specific risk of incident type 2 diabetes in a retrospective primary care cohort. Clinical endocrinology. 2019;90(1):145-54.
  91. Ntouva A, Toulis KA, Keerthy D, Adderley NJ, Hanif W, Thayakaran R, Gokhale K, Thomas GN, Khunti K, Tahrani AA, Nirantharakumar K#. Hypoglycaemia is associated with increased risk of fractures in patients with type 2 diabetes mellitus: a cohort study. European journal of endocrinology. 2019;180(1):51-8.
  92. Mittal A, Hassan ME, Chandan JS, Willis BH, Nirantharakumar K#*, Subramonian K. Cancer as a risk factor for urinary tract calculi: a retrospective cohort study using ‘The Health Improvement Network’. Urolithiasis. 2019;47(6):541-7.
  93. Lavrentaki A, Thomas T, Subramanian A, Valsamakis G, Thomas N, Toulis KA, Wang J, Daly B, Saravanan P, Sumilo D, Mastorakos G, Tahrani AA, Nirantharakumar K#. Increased risk of non-alcoholic fatty liver disease in women with gestational diabetes mellitus: A population-based cohort study, systematic review and meta-analysis. Journal of diabetes and its complications. 2019;33(10):107401.
  94. Kumarendran B, Sumilo D, O’Reilly MW, Toulis KA, Gokhale KM, Wijeyaratne CN, Coomarasamy A, Arlt W, Tahrani AA, Nirantharakumar K#. Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study. European journal of endocrinology. 2019;180(4):265-72.
  95. Harvey PR, Thomas T, Chandan JS, Bhala N, Nirantharakumar K#, Trudgill NJ. Outcomes following feeding gastrostomy (FG) insertion in patients with learning disability: a retrospective cohort study using the health improvement network (THIN) database. BMJ open. 2019;9(6):e026714.
  96. Haider S, Sadiq SN, Moore D, Price MJ, Nirantharakumar K#. Prognostic prediction models for diabetic retinopathy progression: a systematic review. Eye (London, England). 2019;33(5):702-13.
  97. Crowe FL, Thayakaran R, Gittoes N, Hewison M, Thomas GN, Scragg R, Nirantharakumar K#. Non-linear associations of 25-hydroxyvitamin D concentrations with risk of cardiovascular disease and all-cause mortality: Results from The Health Improvement Network (THIN) database. J Steroid Biochem Mol Biol. 2019;195:105480.
  98. Crowe FL, Jolly K, MacArthur C, Manaseki-Holland S, Gittoes N, Hewison M, Scragg R, Nirantharakumar K#. Trends in the incidence of testing for vitamin D deficiency in primary care in the UK: a retrospective analysis of The Health Improvement Network (THIN), 2005-2015. BMJ open. 2019;9(6):e028355.
  99. Chandan JS, Thomas T, Raza K, Bradbury-Jones C, Taylor J, Bandyopadhyay S, Nirantharakumar K#. Intimate Partner Violence and the Risk of Developing Fibromyalgia and Chronic Fatigue Syndrome. J Interpers Violence. 2019:886260519888515.
  100. Chandan JS, Thomas T, Bradbury-Jones C, Taylor J, Bandyopadhyay S, Nirantharakumar K#. Intimate partner violence and temporomandibular joint disorder. Journal of dentistry. 2019;82:98-100.
  101. Adderley NJ, Ryan R, Nirantharakumar K, Marshall T. Prevalence and treatment of atrial fibrillation in UK general practice from 2000 to 2016. Heart. 2019;105(1):27-33.
  102. Adderley N, Nirantharakumar K, Marshall T. Temporal variation in the diagnosis of resolved atrial fibrillation and the influence of performance targets on clinical coding: cohort study. BMJ open. 2019;9(11):e030454.
  103. Wang J, Moore D, Subramanian A, Cheng KK, Toulis KA, Qiu X, Saravanan P, Price MJ, Nirantharakumar K#. Gestational dyslipidaemia and adverse birthweight outcomes: a systematic review and meta-analysis. Obesity reviews : an official journal of the International Association for the Study of Obesity. 2018;19(9):1256-68.
  104. Toulis KA, Robbins T, Reddy N, Balachandran K, Gokhale K, Wijesinghe H, Cheng KK, Karavitaki N, Wass J, Nirantharakumar K#. Males with prolactinoma are at increased risk of incident cardiovascular disease. Clinical endocrinology. 2018;88(1):71-6.
  105. Toulis KA, Jiang CQ, Hemming K, Nirantharakumar K, Cheng KK, Lam TH, Thomas GN. Glycated Hemoglobin, Albuminuria and Surrogate Markers of Macrovascular Disease in Adults Without Diabetes: The Guangzhou Biobank Cohort Study, Cardiovascular Disease Subcohort. Canadian journal of diabetes. 2018;42(3):245-50.e1.
  106. Toulis KA, Jiang CQ, Hemming K, Nirantharakumar K, Cheng KK, Lam TH, Thomas GN. Discriminatory performance of adiponectin and leptin in the identification of impaired glucose tolerance: The Guangzhou Biobank Cohort Study – Cardiovascular Disease Subcohort. PloS one. 2018;13(11):e0206964.
  107. Toulis KA, Bilezikian JP, Thomas GN, Hanif W, Kotsa K, Thayakaran R, Keerthy D, Tahrani AA, Nirantharakumar K#. Initiation of dapagliflozin and treatment-emergent fractures. Diabetes, obesity & metabolism. 2018;20(4):1070-4.
  108. Nirantharakumar K$, Mohammed N, Toulis KA, Thomas GN, Narendran P. Clinically meaningful and lasting HbA(1c) improvement rarely occurs after 5 years of type 1 diabetes: an argument for early, targeted and aggressive intervention following diagnosis. Diabetologia. 2018;61(5):1064-70.
  109. Haroon S, Wooldridge D, Hoogewerf J, Nirantharakumar K, Williams J, Martino L, Bhala N. Information standards for recording alcohol use in electronic health records: findings from a national consultation. BMC medical informatics and decision making. 2018;18(1):36.
  110. Fountas A, Lavrentaki A, Subramanian A, Toulis KA, Nirantharakumar K, Karavitaki N. Recurrence in silent corticotroph adenomas after primary treatment: A systematic review and meta-analysis. The Journal of clinical endocrinology and metabolism. 2018.
  111. Chandan JS, Thomas T, Lee S, Marshall T, Willis B, Nirantharakumar K#*, Gill P. The association between idiopathic thrombocytopenic purpura and cardiovascular disease: a retrospective cohort study. Journal of thrombosis and haemostasis : JTH. 2018;16(3):474-80.
  112. Adderley NJ, Mallett S, Marshall T, Ghosh S, Rayman G, Bellary S, Coleman J, Akiboye F, Toulis KA, Nirantharakumar K#*. Temporal and external validation of a prediction model for adverse outcomes among inpatients with diabetes. Diabetic medicine. 2018;35(6):798-806.
  113. Toulis KA, Willis BH, Marshall T, Kumarendran B, Gokhale K, Ghosh S, Thomas GN, Cheng KK, Narendran P, Hanif W, Nirantharakumar K#. All-Cause Mortality in Patients With Diabetes Under Treatment With Dapagliflozin: A Population-Based, Open-Cohort Study in The Health Improvement Network Database. The Journal of clinical endocrinology and metabolism. 2017;102(5):1719-25.
  114. Toulis KA, Hanif W, Saravanan P, Willis BH, Marshall T, Kumarendran B, Gokhale K, Ghosh S, Cheng KK, Narendran P, Thomas GN, Nirantharakumar K#. All-cause mortality in patients with diabetes under glucagon-like peptide-1 agonists: A population-based, open cohort study. Diabetes & metabolism. 2017;43(3):211-6.
  115. Stuart K, Adderley NJ, Marshall T, Rayman G, Sitch A, Manley S, Ghosh S, Toulis KA, Nirantharakumar K#. Predicting inpatient hypoglycaemia in hospitalized patients with diabetes: a retrospective analysis of 9584 admissions with diabetes. Diabetic medicine. 2017;34(10):1385-91.
  116. Sarwar KN, Cliff P, Saravanan P, Khunti K, Nirantharakumar K*, Narendran P. Comorbidities, complications and mortality in people of South Asian ethnicity with type 1 diabetes compared with other ethnic groups: a systematic review. BMJ open. 2017;7(7):e015005.
  117. Dafoulas GE, Toulis KA, McCorry D, Kumarendran B, Thomas GN, Willis BH, Gokhale K, Gkoutos G, Narendran P, Nirantharakumar K#. Type 1 diabetes mellitus and risk of incident epilepsy: a population-based, open-cohort study. Diabetologia. 2017;60(2):258-61.
  118. Martin J, Girling A, Nirantharakumar K, Ryan R, Marshall T, Hemming K. Intra-cluster and inter-period correlation coefficients for cross-sectional cluster randomised controlled trials for type-2 diabetes in UK primary care. Trials. 2016;17:402.
  119. Wilson A, Nirantharakumar K, Truchanowicz EG, Surenthirakumaran R, MacArthur C, Coomarasamy A. Motivational interviews to improve contraceptive use in populations at high risk of unintended pregnancy: a systematic review and meta-analysis. European journal of obstetrics, gynecology, and reproductive biology. 2015;191:72-9.
  120. Toulis KA, Nirantharakumar K*, Ryan R, Marshall T, Hemming K. Bisphosphonates and glucose homeostasis: a population-based, retrospective cohort study. The Journal of clinical endocrinology and metabolism. 2015;100(5):1933-40.
  121. Toulis KA, Hemming K, Stergianos S, Nirantharakumar K, Bilezikian JP. β-Adrenergic receptor antagonists and fracture risk: a meta-analysis of selectivity, gender, and site-specific effects. Osteoporosis international. 2014;25(1):121-9.
  122. Nwulu U, Nirantharakumar K, Odesanya R, McDowell SE, Coleman JJ. Improvement in the detection of adverse drug events by the use of electronic health and prescription records: an evaluation of two trigger tools. European journal of clinical pharmacology. 2013;69(2):255-9.
  123. Nirantharakumar K$, Toulis KA, Wijesinghe H, Mastan MS, Srikantharajah M, Bhatta S, Marshall T, Coleman JJ. Impact of diabetes on inpatient mortality and length of stay for elderly patients presenting with fracture of the proximal femur. Journal of diabetes and its complications. 2013;27(3):208-10.
  124. Nirantharakumar K$*, Saeed M, Wilson I, Marshall T, Coleman JJ. In-hospital mortality and length of stay in patients with diabetes having foot disease. Journal of diabetes and its complications. 2013;27(5):454-8.
  125. Mohammed MA, Marshall T, Nirantharakumar K, Stevens A, Fitzmaurice D. Patterns of warfarin use in subgroups of patients with atrial fibrillation: a cross-sectional analysis of 430 general practices in the United Kingdom. PloS one. 2013;8(5):e61979.
  126. Makura CB, Nirantharakumar K, Girling AJ, Saravanan P, Narendran P. Effects of physical activity on the development and progression of microvascular complications in type 1 diabetes: retrospective analysis of the DCCT study. BMC endocrine disorders. 2013;13:37.
  127. Kennedy A, Nirantharakumar K, Chimen M, Pang TT, Hemming K, Andrews RC, Narendran P. Does exercise improve glycaemic control in type 1 diabetes? A systematic review and meta-analysis. PloS one. 2013;8(3):e58861.
  128. Nirantharakumar K$*, Marshall T, Kennedy A, Narendran P, Hemming K, Coleman JJ. Hypoglycaemia is associated with increased length of stay and mortality in people with diabetes who are hospitalized. Diabetic medicine. 2012;29(12):e445-8.
  129. Nirantharakumar K$*, Marshall T, Hodson J, Narendran P, Deeks J, Coleman JJ, Ferner RE. Hypoglycemia in non-diabetic in-patients: clinical or criminal? PloS one. 2012;7(7):e40384.
  130. Nirantharakumar K$*, Marshall T, Hemming K, Narendran P, Coleman JJ. Inpatient electronic prescribing data can be used to identify ‘lost’ discharge codes for diabetes. Diabetic medicine.2012;29(12):e430-5.
  131. Nirantharakumar K$*, Chen YF, Marshall T, Webber J, Coleman JJ. Clinical decision support systems in the care of inpatients with diabetes in non-critical care setting: systematic review. Diabetic medicine : a journal of the British Diabetic Association. 2012;29(6):698-708.
  132. Wijeyaratne CN, Nirantharakumar K, Balen AH, Barth JH, Sheriff R, Belchetz PE. Plasma homocysteine in polycystic ovary syndrome: does it correlate with insulin resistance and ethnicity? Clinical endocrinology. 2004;60(5):560-7.

 

Published protocols, correspondence, literature reviews and editorials

  1. Haroon S, Nirantharakumar K, Hughes SE, Subramanian A, Aiyegbusi OL, Davies EH, Myles P, Williams T, Turner G, Chandan JS, McMullan C, Lord J, Wraith DC, McGee K, Denniston AK, Taverner T, Jackson LJ, Sapey E, Gkoutos G, Gokhale K, Leggett E, Iles C, Frost C, McNamara G, Bamford A, Marshall T, Zemedikun DT, Price G, Marwaha S, Simms-Williams N, Brown K, Walker A, Jones K, Matthews K, Camaradou J, Saint-Cricq M, Kumar S, Alder Y, Stanton DE, Agyen L, Baber M, Blaize H, Calvert M. Therapies for Long COVID in non-hospitalised individuals: from symptoms, patient-reported outcomes and immunology to targeted therapies (The TLC Study). BMJ open. 2022;12(4):e060413.
  2. Quinn LM, Thayakaran R, Thomas N, Nirantharakumar K, Narendran P. Comment on Lachin et al. The Beneficial Effects of Earlier Versus Later Implementation of Intensive Therapy in Type 1 Diabetes. Diabetes Care 2021;44:2225-2230. Diabetes care. 2022;45(3):e70-e1.
  3. Chandan JS, Brown K, Simms-Williams N, Camaradou J, Bashir N, Heining D, Aiyegbusi OL, Turner G, Cruz Rivera S, Hotham R, Nirantharakumar K, Sivan M, Khunti K, Raindi D, Marwaha S, Hughes SE, McMullan C, Calvert M, Haroon S. Non-pharmacological therapies for postviral syndromes, including Long COVID: a systematic review and meta-analysis protocol. BMJ open. 2022;12(4):e057885.
  4. Antza C, Kostopoulos G, Mostafa S, Nirantharakumar K, Tahrani A. The links between sleep duration, obesity and type 2 diabetes mellitus. J Endocrinol. 2021;252(2):125-41.
  5. Simms-Williams N, Nagakumar P, Thayakaran R, Adderley N, Hotham R, Mansur A, Nirantharakumar K, Haroon S. Preventing unscheduled hospitalisations from asthma: a retrospective cohort study using routine primary and secondary care data in the UK (The PUSH-Asthma Study)-protocol paper. BMJ open. 2022;12(8):e058356.
  6. Coomar D, Hazlehurst JM, Austin F, Foster C, Hitman GA, Heslehurst N, Iliodromiti S, Betran AP, Moss N, Poston L, Nirantharakumar K, Roberts T, Simpson SA, Teede HJ, Riley R, Allotey J, Thangaratinam S. Diet and physical activity in pregnancy to prevent gestational diabetes: a protocol for an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation. BMJ open. 2021;11(6):e048119.Goel R, Chandan JS, Thayakaran R, Adderley NJ, Nirantharakumar K, Harper L. Reply. Arthritis Rheumatol. 2021;73(11):2145-6.
  7. Lee SI, Eastwood KA, Moss N, Azcoaga-Lorenzo A, Subramanian A, Anand A, Taylor B, Nelson-Piercy C, Yau C, McCowan C, O’Reilly D, Hope H, Kennedy JI, Abel KM, Locock L, Brocklehurst P, Plachcinski R, Brophy S, Agrawal U, Thangaratinam S, Nirantharakumar K, Black M. Protocol for the development of a core outcome set for studies of pregnant women with pre-existing multimorbidity. BMJ open. 2021;11(10):e044919.
  8. Torlinska B, Hazlehurst JM, Nirantharakumar K, Thomas GN, Priestley JR, Finnikin SJ, Saunders P, Abrams KR, Boelaert K. wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study. BMJ open. 2021;11(10):e055219.
  9. Perros P, Nirantharakumar K, Hegedüs L. Recent evidence sets therapeutic targets for levothyroxine-treated patients with primary hypothyroidism based on risk of death. European journal of endocrinology. 2021;184(2):C1-c3.
  10. Goel R, Chandan JS, Thayakaran R, Adderley NJ, Nirantharakumar K, Harper L. Reply. Arthritis Rheumatol. 2021;73(10):1948-50.
  11. Chandan JS, Taylor J, Bradbury-Jones C, Nirantharakumar K, Kane E, Bandyopadhyay S. COVID-19: a public health approach to manage domestic violence is needed. Lancet Public Health. 2020;5(6):e309.
  12. Toulis KA, Nirantharakumar K, Pourzitaki C, Barnett AH, Tahrani AA. Glucokinase Activators for Type 2 Diabetes: Challenges and Future Developments. Drugs. 2020;80(5):467-75.
  13. Chandan JS, Bandyopadhyay S, Taylor J, Nirantharakumar K. Gender differences in the presentation of fibromyalgia amongst children who have been maltreated. EClinicalMedicine. 2020;25:100469.
  14. Adderley N, Singh P, Tahrani AA, Nirantharakumar K. Author response to: Comment on: Impact of bariatric surgery on cardiovascular outcomes and mortality: a population-based cohort study. Br J Surg. 2020;107(7):e220.
  15. Antza C, Nirantharakumar K, Doundoulakis I, Tahrani AA, Toulis KA. The development of an oral GLP-1 receptor agonist for the management of type 2 diabetes: evidence to date. Drug Des Devel Ther. 2019;13:2985-96.
  16. Lip GYH, Guo Y, Lotufo P, Surenthirakumaran R, Humphreys L, Thomas GN on behalf of the The National Institute for Health Research (NIHR) Global Health Research Group on Atrial Fibrillation management. Eur Heart J. 2019;40(36):3005-7.
  17. Bhachu HK, Cockwell P, Subramanian A, Nirantharakumar K, Kyte D, Calvert M. Cross-sectional observation study to investigate the impact of risk-based stratification on care pathways for patients with chronic kidney disease: protocol paper. BMJ open. 2019;9(6):e027315.
  18. Šumilo D, Nirantharakumar K, Willis BH, Rudge G, Martin J, Gokhale K, Thayakaran R, Adderley NJ, Chandan JS, Okoth K, Hewston R, Skrybant M, Deeks JJ, Brocklehurst P. Long-term impact of giving antibiotics before skin incision versus after cord clamping on children born by caesarean section: protocol for a longitudinal study based on UK electronic health records. BMJ open. 2019;9(9):e033013.
  19. Chandan JS, Thomas T, Raza K, Bandyopadhyay S, Nirantharakumar K, Taylor J. Association between child maltreatment and central sensitivity syndromes: a systematic review protocol. BMJ open. 2019;9(2):e025436.
  20. Caleyachetty R, Nirantharakumar K, Thomas GN. Reply: Is Metabolically Healthy Obesity a Harmless Condition? Journal of the American College of Cardiology. 2018;71(7):816-7.
  21. Chimen M, Kennedy A, Nirantharakumar K, Pang TT, Andrews R, Narendran P. What are the health benefits of physical activity in type 1 diabetes mellitus? A literature review. Diabetologia. 2012;55(3):542-51.
  22. Tracy A, Subramanian A, Adderley NJ, Harper L, Nirantharakumar K. Response to ‘IgA vasculitis in adults: few certainties and many uncertainties’ by Hočevar et al. Annals of the rheumatic diseases. 2020;79(4):e48.
  23. Nirantharakumar K. Screening for congenital heart disease with newborn pulse oximetry. Lancet (London, England). 2012;379(9813):310-1; author reply 1.
  24. Nirantharakumar K, Marshall T. Polypill: the path from concept to “near” reality in preventing cardiovascular disease. Archives of Iranian medicine. 2012;15(10):659-60; author reply 60.

Diabetes

Health informatics

Chronic disease

Management

Endocrinology